Concepedia

Segregation analysis of hepatocellular carcinoma in a moderately high-incidence area of East China

Ru-lin Cai, Meng Wei, Hongyan Lu, Wenyao Lin, Feng Jiang, Fumin Shen

World Journal of Gastroenterology · 2003 · 40 citations · 25 references

DOIFull text

Open access

Abstract

These results suggest that at least one major gene is involved in the genetic predisposition to develop HCC at an earlier age of onset. The seropositive HBsAg status can significantly increase the risk of developing HCC, which provides strong support for the interaction between genetic and environmental risk factors.

References

25

Epidemiology, Risk Factors, and Natural History of Hepatocellular Carcinoma

Giuseppe Montalto, Melchiorre Cervello, Lydia Giannitrapani et al. · Annals of the New York Academy of Sciences · 2002 · 306 citations

Familial Risk of Hepatocellular Carcinoma Among Chronic Hepatitis B Carriers and Their Relatives

Ming‐Whei Yu · JNCI Journal of the National Cancer Institute · 2000 · 233 citations · Full text

Dominant role of hepatitis B virus and cofactor role of aflatoxin in hepatocarcinogenesis in Qidong, China

Lihua Ming, Snorri S. Thorgeirsson, Mitchell H. Gail et al. · Hepatology · 2002 · 229 citations · Full text

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Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection in Japan: Projection to Other Countries in the Foreseeable Future

Hiroshi Yoshizawa · Oncology · 2002 · 227 citations

, , +23

Eight-year follow-up of the 90,000-person Haimen City cohort: I. Hepatocellular carcinoma mortality, risk factors, and gender differences.

Alison A. Evans, Gang Chen, Eric A. Ross et al. · PubMed · 2002 · 209 citations

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