Cyclosporine-induced hypertension. Efficacy of omega-3 fatty acids in patients after cardiac transplantation.

Abstract

omega-3 Fatty acids (3 g/d) reduce blood pressure by decreasing systemic vascular resistance and, therefore, can be used as an adjuvant for the treatment of hypertension in cyclosporine-treated cardiac transplant recipients. Their vasodilatory effect may be related to a beneficial change in the prostaglandin profile.