A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

Ralf Schreck, P. Rieber, Patrick A. Baeuerle · The EMBO Journal · 1991 · 3.8K citations · Full text

Inflammation, Cytokine, Transcriptional Regulation +13

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

Ranjan Sen, David Baltimore · Cell · 1986 · 2K citations

Transcriptional Regulation, Molecular Immunology, Signal Transduction +14

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

Ralf Schreck, Beate Meier, Daniela N. Männel et al. · The Journal of Experimental Medicine · 1992 · 1.5K citations · Full text

Intact Cells, Antioxidant Pdtc, Immunology +21

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

Sankar Ghosh, David Baltimore · Nature · 1990 · 1.2K citations

Inflammation, Cytokine, Inhibitor Iκb +11

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

Patrick A. Baeuerle, D Baltimore · Cell · 1988 · 1.2K citations

Transcriptional Regulation, Signal Transduction, Cell Regulation +15