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High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies

Synthetic OligomersBiochemistryNatural SciencesDrug DiscoveryMedicineBioconjugationHigh Affinity BindingMolecular BiologyPeptide EngineeringMurine Type 1Protein EngineeringAntibody EngineeringNon-peptide LigandMolecular DockingBiomolecular Engineering