Involvement of multiple pathways in the protection of liver against high-fat diet-induced steatosis by betaine

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

Life Sciences, Endocrinology, Pharmacology +16

Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

Shi Qi Yang, Hui Lin, M. Daniel Lane et al. · Proceedings of the National Academy of Sciences · 1997 · 810 citations

Life Sciences, Immunology, Pathobiology +17

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

Sean B. Joseph, Bryan Laffitte, Parthive H. Patel et al. · Journal of Biological Chemistry · 2002 · 764 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

Geoff H. Werstuck, Steven R. Lentz, Sanjana Dayal et al. · Journal of Clinical Investigation · 2001 · 705 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

Julie McGarry, Stanley E. Mills, Carlin S. Long et al. · Biochemical Journal · 1983 · 556 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +9