Enhancing Student Mental Health: Collaboration between Medical Professionals and School Psychologists.

Abstract

Exposure of dichlorovinyl ethers <b>1</b> to <i>n-</i>butyllithium and addition of saturated or unsaturated aldehydes, ketones, or esters at ambient temperature furnishes rearranged α,β-unsaturated carboxylic acids, isolated as their corresponding methyl esters <b>2</b> in 48-91% overall yields. Exposure of dichlorovinyl ethers <b>1</b> to <i>n-</i>butyllithium, addition of aldehydes, ketones, dialdehydes, or diketones at -78 °C, and warming to 80 °C in the presence of SiO₂ provide 1,4-dienes <b>3</b> or cycloalken-1-ols (or their dehydration products) <b>4</b> in 45-72% overall yields.