Concepedia

Peroxisome proliferator activated receptor-γ in pathogenesis of experimental fatty liver disease

Caiyan Zhao, Lingling Jiang, Li Li, Zhuojun Deng, Bao-Li Liang, Jian‐Mei Li

World Journal of Gastroenterology · 2004 · 30 citations · 16 references

DOIFull text

Open access

Abstract

Decreased expression of PPARgamma may play an important role in the development of hepatocellular inflammation, necrosis and fibrosis of rats with FLD. Thus, activating PPARgamma by its ligand can be anticipated to provide a therapy target for FLD.

References

16

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NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome

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Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver Due to Peroxisome Proliferator-activated Receptor γ1 (PPARγ1) Overexpression

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Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation

Takeo Miyahara, Laura W. Schrum, Richard A. Rippe et al. · Journal of Biological Chemistry · 2000 · 468 citations · Full text