Phytochemical constituents of Carpesium macrocephalum F(R). et S(AV).

Abstract

From the methanol extract of the whole plants ofCarpesium macrocephalum FR. et SAV., five sesquiterpene lactones (1: carabron,2: tomentosin,3: ivalin,4: 4H-tomentosin,5: carabrol) and three terpenoids (6: loliolide,7: vomifoliol,8: citrusin C) were isolated. The structures and stereochemistry of compounds1-8 were established on the basis of chemical analysis as well as 1D- and 2D-NMR spectroscopy. Among them, compounds2, 4, and6-8 were isolated for the first time fromCarpesium species.