2011 · 923 citations · 94 references
Life SciencesBotanyPharmacologyEthnobotanyMetabolomicsPlant BiochemistryBioactive Food ComponentsMedicinal Plant KnowledgeMedicinal PlantsAntioxidant PropertiesHerbal SupplementsMass Spectrometry ProteomicsMedicinal HerbsOxidative Stress InjuryPhytochemical CompositionPlant-based RemediesTraditional Herbal Medicine
Herbal supplements are globally popular, prompting intense interest in their molecular mechanisms and a growing demand for rigorous scientific evaluation to support effective, affordable health promotion, especially among an aging population. The volume aims to present current scientific evidence on the biomolecular effects of selected herbs, their clinical outcomes, ethical considerations, and integration into evidence‑based medicine, with a focus on antioxidant properties. It examines individual herb effects and therapeutic applications across diseases, covering diverse herb types, and employs mass spectrometry and chemometric fingerprinting to authenticate herbal extracts. The volume provides a comprehensive, timely resource for medical professionals, researchers, and complementary medicine enthusiasts.
The global popularity of herbal supplements and the promise they hold in treating various disease states have caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. This volume focuses on presenting current scientific evidence of biomolecular effects of selected herbs and their relation to clinical outcome and promotion of human health. This book also addresses the ethical challenges of using herbal medicine and its integration into modern, evidence-based medicine.Drawing from the work of leading international researchers in different fields, this book contains an in-depth scientific examination of effects of individual herbs, as well as their use in the treatment of important diseases such as cancer, cardiovascular disease, dermatologic disorders, neurodegenerative disease, and diabetes. Due to the strong associations among oxidative stress, ageing, and disease, the powerful antioxidant properties of herbs and spices are also examined. The herbs featured are some of the most widely used remedies and cover a wide range, including flowering herbs, fruits and berries, roots and rhizomes, and fungi.To help bring a new level of quality control to the production of herbal extracts, the use of mass spectrometry and chemometric fingerprinting technology in the authentication of herbs is also presented. As the need for effective, affordable health promotion and treatment increases, especially in the growing ageing population, there is demand for rigorous scientific examination of herbal medicines. This timely and comprehensive volume addresses this need and is an important text for medical professionals and researchers, as well as those interested in herbal or complementary medicine.
94
The Influence of Finasteride on the Development of Prostate Cancer
Ian M. Thompson, Phyllis J. Goodman, Catherine M. Tangen et al. · New England Journal of Medicine · 2003 · 2.5K citations · Full text
John P. Bilezikian, Maria Luisa Brandi, Richard Eastell et al. · The Journal of Clinical Endocrinology & Metabolism · 2014 · 1.3K citations · Full text
Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids).
Michael B. Sporn, Nancy M. Dunlop, Dianne L. Newton et al. · PubMed · 1976 · 993 citations
Medicine, Oncology, Pharmacology +13
Incidence of drug-induced hepatic injuries: A French population-based study
Catherine Sgro, François Clinard, Kader Ouazir et al. · Hepatology · 2002 · 841 citations