Up-Regulation of Cyclooxygenase-2 by Product-Prostaglandin E2

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

Dean A. Kujubu, Bradley S. Fletcher, Brian Varnum et al. · Journal of Biological Chemistry · 1991 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

Wei Xie, Jeffrey G. Chipman, Donald Robertson et al. · Proceedings of the National Academy of Sciences · 1991 · 1.7K citations

Life Sciences, Biochemistry, Molecular Biology +16

Aspirin Use and Reduced Risk of Fatal Colon Cancer

Michael J. Thun, Mohan M. Namboodiri, Clark W. Heath · New England Journal of Medicine · 1991 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +12

Structure of the human cyclo-oxygenase-2 gene

Susan B. Appleby, Ari Ristimäki, Karen M. Neilson et al. · Biochemical Journal · 1994 · 482 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.

Ari Ristimäki, Susan Garfinkel, J Wessendorf et al. · Journal of Biological Chemistry · 1994 · 475 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17