Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

Medicine, Cancer Biology, Oncology +16

Methods in Mammalian Autophagy Research

Noboru Mizushima, Tamotsu Yoshimori, Beth Levine · Cell · 2010 · 4.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Geir Bjørkøy, Trond Lamark, Andreas Brech et al. · The Journal of Cell Biology · 2005 · 3.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

Fadi Jacob, Ryan Salinas, Daniel Y. Zhang et al. · Cell · 2019 · 1.1K citations · Full text

Medicine, Cancer Biology, Oncology +16

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

Xiaowei Ma, Yanyang Wu, Shubin Jin et al. · ACS Nano · 2011 · 625 citations

Life Sciences, Cell Biology, Materials Science +15