Natural Product Research · 2015 · 24 citations · 14 references
Medicinal ChemistryTricyclic Abietane DiterpenoidBioorganic ChemistryEngineeringBiochemistryDerivative (Chemistry)Natural SciencesOrganic ChemistryPhytochemicalPhytochemistryPharmacologyKetal FunctionalityCompound 1Abietane DiterpenoidBiomolecular EngineeringNatural Product Synthesis
Phytochemical investigation of the roots of Salvia chloroleuca led to the isolation and identification of a new rearranged abietane diterpenoid (1). Its structure was elucidated by interpretation of the 1D and 2D NMR spectra and completed by the analysis of the HR-ESI-MS data. Compound 1 is the secondly reported compound on a rearranged tricyclic abietane (4,5-seco-5,10-friedo-abietane) diterpenoid with a ketal functionality between C-2 and C-11. A plausible biosynthetic pathway of 1 was also proposed.
14