The effects of <i>cis</i> and <i>trans</i> butenedioic acid on the physicochemical behavior of lumefantrine

Abstract

A study of the differences in the effects of cis (maleic acid) and trans (fumaric acid) isomers of butenedioic acid on the crystallinity, amorphous nature, and pharmaceutical behaviour of the antimalarial drug lumefantrine is provided.