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Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1

Structural BioinformaticsMolecular Biological MethodNatural SciencesMolecular BiologyDna ReplicationDna Ligase 1Structure-based ScreeningBiochemical AnalysesMedicineFunctional GenomicsGenome EditingStructural BiologyBiomolecular Engineering