Concepedia

Recognition of Variants of Concern by Antibodies and T Cells Induced by a SARS-CoV-2 Inactivated Vaccine

Felipe Melo-González, Jorge A. Soto, Liliana A González, Jorge Onrubia Fernández, Luisa F. Duarte, Bárbara M. Schultz, Nicolás M. S. Gálvez, Gaspar A. Pacheco, Mariana Ríos, Yaneisi Vázquez,

Frontiers in Immunology · 2021 · 80 citations · 34 references

DOIFull text

Open access

Abstract

Immunization with CoronaVac in either immunization schedule promotes the secretion of antibodies able to block SARS-CoV-2 variants of concern and partially neutralizes SARS-CoV-2 infection. In addition, it stimulates cellular responses against all variants of concern.

References

34

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David S. Khoury, Deborah Cromer, Arnold Reynaldi et al. · Nature Medicine · 2021 · 4.1K citations · Full text

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Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

Delphine Planas, David Veyer, Artem Baidaliuk et al. · Nature · 2021 · 2.2K citations · Full text

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Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

Yanjun Zhang, Gang Zeng, Hongxing Pan et al. · The Lancet Infectious Diseases · 2020 · 1.5K citations · Full text

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Chee Wah Tan, Wan Ni Chia, Xijian Qin et al. · Nature Biotechnology · 2020 · 1.3K citations · Full text

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

Lizhou Zhang, Cody B. Jackson, Huihui Mou et al. · Nature Communications · 2020 · 1.1K citations · Full text