Concepedia

ERK1/2-mediated activation of DRP1 regulates mitochondrial dynamics and apoptosis in chondrocytes

Mohammad Y. Ansari, Kerri L. Novak, Tariq M. Haqqi

Osteoarthritis and Cartilage · 2021 · 92 citations · 32 references

DOIFull text

Open access

Concepts

References

32

Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Lorena Griparić, Dixie‐Lee Shurland, Alexander M. van der Bliek · Molecular Biology of the Cell · 2001 · 1.9K citations · Full text

, , +17

The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

Stephan Frank, Brigitte Gaume, Elke S. Bergmann‐Leitner et al. · Developmental Cell · 2001 · 1.7K citations · Full text

, , +13

Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

Tianzheng Yu, James L. Robotham, Yisang Yoon · Proceedings of the National Academy of Sciences · 2006 · 1.2K citations · Full text

, , +17

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

Oliver C. Losón, Zhiyin Song, Hsiuchen Chen et al. · Molecular Biology of the Cell · 2013 · 1.2K citations · Full text

, , +16

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

Ann Cassidy-Stone, Jerry E. Chipuk, Elena Ingerman et al. · Developmental Cell · 2008 · 1.2K citations · Full text

, , +16