Ketamine for the treatment of acute pain

Abstract

Ketamine is a phencyclidine (PCP) derivative that exerts its effects primarily through N -methyl-d-aspartate receptor inhibition.[1][1] At low doses (0.1–0.3 mg/kg), ketamine produces mainly analgesia. Dissociative anesthesia and psychomimetic effects occur with higher doses (≥ 1.0 mg/kg). Low-