Concepedia

Deciphering the AChE-binding mechanism with multifunctional tricyclic coumarin anti-Alzheimer's agents using biophysical and bioinformatics approaches and evaluation of their modulating effect on Amyloidogenic peptide assembly

Jeelan Basha Shaik, Yelamanda Rao Kandrakonda, Monika Kallubai, Navya Naidu Gajula, Shreya Dubey, Bindu Madhava Reddy Aramati, Rajagopal Subramanyam, Gangaiah Damu Amooru

International Journal of Biological Macromolecules · 2021 · 17 citations · 39 references

References

39

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

Sander Pronk, Szilárd Páll, Roland Schulz et al. · Bioinformatics · 2013 · 7.6K citations · Full text

Natural Sciences, Chemistry, High-performance Computing +17

2016 Alzheimer's disease facts and figures

Alzheimer s & Dementia · 2016 · 5.1K citations

Medicine, Geriatric Medicine, Population Health Sciences +17

<i>PRODRG</i>: a tool for high-throughput crystallography of protein–ligand complexes

Alexander W. Schüttelkopf, Daan M. F. van Aalten · Acta Crystallographica Section D Biological Crystallography · 2004 · 4.8K citations · Full text

Life Sciences, Medicinal Chemistry, Computational Chemistry +16

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti et al. · Nature · 2002 · 2.4K citations

Life Sciences, Biochemistry, Molecular Biology +17

2018 Alzheimer's disease facts and figures

Alzheimer s & Dementia · 2018 · 1.9K citations

Medicine, Geriatric Medicine, Neurology +17