Environmental Science Processes & Impacts · 2021 · 11 citations · 33 references
MedicineBiochemistryPharmacologyDrug MetabolismMetabolismCytochrome P450 EnzymesCytochrome P450-mediated MetabolismMetabolic ActivationCyp2a6 MetabolismCytochrome P450 Enzyme ActivityCytochrome P450 OxidationCytochrome P450 Reaction MechanismsIndirect Exposure AssessmentPhase I Metabolic Activation
value. Collectively, these findings provide a mechanistic perspective on the potential importance of CYP2A6 in the metabolic activation and phase I elimination of 6:2 FTOH and indirect human exposure to PFCAs.
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