Concepedia

Interruption of neutrophil extracellular traps formation dictates host defense and tubular HOXA5 stability to augment efficacy of anti-Fn14 therapy against septic AKI

Ni Yin, Bangchuan Hu, Guohua Wu, Ziqiang Shao, Yang Zheng, Run Zhang, Jun Jin, Jun Hong, Xianghong Yang, Ren-Hua Sun,

Theranostics · 2021 · 38 citations · 31 references

DOIFull text

Open access

Concepts

Abstract

Our preclinical data propose that interrupting NETs formation in combination with Fn14 mAb might be a feasible therapeutic strategy for septic AKI.

References

31

Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Yi Chen, Lei Wang, Qiuxiang Kang et al. · Cellular Physiology and Biochemistry · 2017 · 10.7K citations · Full text

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Neutrophil Extracellular Traps Kill Bacteria

Volker Brinkmann, Ulrike Reichard, Christian Goosmann et al. · Science · 2004 · 10.1K citations

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JASPAR 2020: update of the open-access database of transcription factor binding profiles

Oriol Fornés, Jaime A. Castro-Mondragón, Aziz Khan et al. · Nucleic Acids Research · 2019 · 1.9K citations · Full text

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NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

Ritika Khandpur, Carmelo Carmona‐Rivera, Anuradha Vivekanandan‐Giri et al. · Science Translational Medicine · 2013 · 1.3K citations

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Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination

Yanming Wang, Joanna Wysocka, Joyce Sayegh et al. · Science · 2004 · 995 citations

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