Biomedical & Pharmacology Journal · 2021 · 10 citations · 22 references
Veterinary MedicineBiotechnologyInfectious DiseasesImmunizationVaccinologyVirologyVaccinationVaccine DevelopmentVaccine PlatformsVaccine-preventable DiseasesViral VaccinesViral Vector VaccinesCoronavirus VaccinesInfectious Disease VaccinesPlatform Vaccine TechnologiesTrial Status Updates
The Covid-19 pandemic since 2019 has imparted a massive influence on the human life around the world, irrespective of all the precautionary measures followed worldwide it is strongly suggested that only the effective and safer vaccine can control this vicious pandemic. Nevertheless, the vaccine development strategies for Covid-19 was initiated firstly in china after the outbreak of Covid-19 and then globally after it was declared as pandemic by World Health Organization. Currently, numerous platforms have been designed for developing the most efficacious and safe vaccines designed by different technologies including protein subunit, viral vector, RNA, DNA, inactivated, and live attenuated approach. Here, this review will illustrates the detailed information on above mentioned Covid-19 vaccines development technologies, protocols and their clinical trial phase status. Additionally, this review also includes the details of vaccines failed to progress further.
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Cell entry mechanisms of SARS-CoV-2
Jian Shang, Yushun Wan, Chuming Luo et al. · Proceedings of the National Academy of Sciences · 2020 · 3.5K citations · Full text
Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections
Quanxin Long, Xiao-Jun Tang, Q L Shi et al. · Nature Medicine · 2020 · 3.1K citations · Full text
Longitudinal analyses reveal immunological misfiring in severe COVID-19
Carolina Lucas, Patrick Wong, Jon Klein et al. · Nature · 2020 · 2.3K citations · Full text