Concepedia

Classical and Non-classical Fibrosis Phenotypes Are Revealed by Lung and Cardiac Like Microvascular Tissues On-Chip

Akinola Akinbote, Violeta Beltrán-Sastre, Marta Cherubini, Roberta Visone, Cynthia Hajal, Defne Cobanoglu, Kristina Haase

Frontiers in Physiology · 2021 · 26 citations · 44 references

DOIFull text

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Concepts

Abstract

model has the potential to examine anti-fibrotic therapies on patient-specific hiPSCs in the future.

References

44

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

Elisabeth M. Zeisberg, Oleg Tarnavski, Michael Zeisberg et al. · Nature Medicine · 2007 · 2.2K citations

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Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity

Boris Hinz, Giuseppe Celetta, James J. Tomasek et al. · Molecular Biology of the Cell · 2001 · 1.3K citations

, , +17

Cross-tissue organization of the fibroblast lineage

Matthew B. Buechler, Rachana Pradhan, Akshay T. Krishnamurty et al. · Nature · 2021 · 1.1K citations

, , +14

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

Elisabeth M. Zeisberg, Scott Potenta, Liang Xie et al. · Cancer Research · 2007 · 972 citations

, , +17

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

Vivian Barry-Hamilton, Rhyannon Spangler, Derek Marshall et al. · Nature Medicine · 2010 · 855 citations

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