Dietary ω-3 polyunsaturated fatty acids are protective for myopia

Abstract

Significance Myopia is a leading cause of visual impairment. However, a safe and accessible approach for myopia control is currently unavailable. In the present study, we demonstrated that dietary supplements of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) attenuated myopia development in animal models. ω-3 PUFAs also ameliorated near-work–induced decreases in choroidal blood perfusion in young adults. Hence, when safety and effectiveness have been confirmed in future clinical studies, ω-3 PUFAs should be attractive candidates for myopia control in humans.