Concepedia

Therapeutic potential of garlic chive-derived vesicle-like nanoparticles in NLRP3 inflammasome-mediated inflammatory diseases

Baolong Liu, Xingzhi Li, Han Vit Yu, Xuan Shi, You Zhou, Sophie Alvarez, Michael J. Naldrett, Stephen D. Kachman, Seung‐Hyun Ro, Xinghui Sun,

Theranostics · 2021 · 111 citations · 56 references

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Concepts

Abstract

Identification of GC-VLNs and their active component DLPC as potent inflammasome inhibitors provides new therapeutic candidates in the treatment of NLRP3 inflammasome-driven diseases.

References

56

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Théry, Kenneth W. Witwer, Elena Aïkawa et al. · Journal of Extracellular Vesicles · 2018 · 11.2K citations · Full text

, , +13

NF-κB signaling in inflammation

Ting Liu, Lingyun Zhang, Donghyun Joo et al. · Signal Transduction and Targeted Therapy · 2017 · 8.1K citations · Full text

, , +17

Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

Patrice D. Cani, Jacques Amar, Miguel A. Iglesias et al. · Diabetes · 2007 · 6.4K citations · Full text

, , +17

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

, , +11

Tumour exosome integrins determine organotropic metastasis

Ayuko Hoshino, Bruno Costa‐Silva, Tang‐Long Shen et al. · Nature · 2015 · 5.1K citations · Full text

, , +14