Nutrition & Metabolism · 2021 · 48 citations · 44 references
Betanin could modulate AMPK/SIRT1/NF-κB signaling pathway and this may be one of its anti-diabetic molecular mechanisms.
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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.1K citations · Full text
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.6K citations · Full text