Concepedia

Multifunctional P-ligand-controlled “silicon-centered” selectivity in Rh/Cu-catalyzed Si–C bond cleavage of silacyclobutanes

Xu Wang, Shuaishuai Huang, Fengjiao Zhang, Jiale Xie, Zhao Li, Zheng Xu, Fei Ye, Li‐Wen Xu

Organic Chemistry Frontiers · 2021 · 67 citations · 37 references

DOI

Concepts

Abstract

A newly developed Ar-BINMOL-Phos-controlled Rh/Cu-catalyzed (4+2) annulation of silacylcobutanes with arylpropiolate-type internal alkynes gave silicon-stereogenic 1-sila-2-cyclohexene derivatives with good ee and excellent chemoselectivity.

References

37

Organosilicon Molecules with Medicinal Applications

Annaliese K. Franz, Sean O. Wilson · Journal of Medicinal Chemistry · 2012 · 1.1K citations · Full text

, , +17

Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life

S. B. Jennifer Kan, Russell D. Lewis, Kai Chen et al. · Science · 2016 · 578 citations

, , +17

Palladium-Catalyzed Enantioselective Desymmetrization of Silacyclobutanes: Construction of Silacycles Possessing a Tetraorganosilicon Stereocenter

Ryo Shintani, Kohei Moriya, Tamio Hayashi · Journal of the American Chemical Society · 2011 · 217 citations

, , +10

Silicon-Stereogenic Silanes in Asymmetric Catalysis

Martin Oestreich · Synlett · 2007 · 197 citations

, , +12

Asymmetric Synthesis of Silicon‐Stereogenic Vinylhydrosilanes by Cobalt‐Catalyzed Regio‐ and Enantioselective Alkyne Hydrosilylation with Dihydrosilanes

Huanan Wen, Xiaolong Wan, Zheng Huang · Angewandte Chemie International Edition · 2018 · 193 citations

, , +11