Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition

Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney

Seok Ho, Takashi Sekine, Junichi Fukushima et al. · Molecular Pharmacology · 2001 · 504 citations

Life Sciences, Nephrology, Physiology +10

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

Mikko Niemi, Janne T. Backman, Mikko Neuvonen et al. · Diabetologia · 2003 · 279 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +8

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

Sanjay K. Nigám, Wei Wu, Kevin T. Bush et al. · Clinical Journal of the American Society of Nephrology · 2015 · 262 citations

Medicine, Nephrology, Pharmacology +17

Untargeted Metabolomics Identifies Enterobiome Metabolites and Putative Uremic Toxins as Substrates of Organic Anion Transporter 1 (Oat1)

William R. Wikoff, Megha Nagle, Valentina L. Kouznetsova et al. · Journal of Proteome Research · 2011 · 181 citations

Life Sciences, Biochemistry, Pharmacology +15

Quantitative Prediction of Human Renal Clearance and Drug-Drug Interactions of Organic Anion Transporter Substrates Using In Vitro Transport Data: A Relative Activity Factor Approach

Sumathy Mathialagan, Mary Piotrowski, David A. Tess et al. · Drug Metabolism and Disposition · 2017 · 128 citations

Pharmacy, Pharmacokinetics, Pharmacology +17