Lowering the viscosity of a high-concentration antibody solution by protein–polyelectrolyte complex

Challenges in the development of high protein concentration formulations

Zahra Shahrokh, Jun 军 Liu 刘 · Journal of Pharmaceutical Sciences · 2004 · 855 citations

Reversible Self-Association Increases the Viscosity of a Concentrated Monoclonal Antibody in Aqueous Solution

Jun Liu, Mary D.H. Nguyen, James D. Andya et al. · Journal of Pharmaceutical Sciences · 2005 · 433 citations

Concentrated Monoclonal Antibody, Aqueous Solution, Glycobiology +8

The Influence of Charge Distribution on Self-Association and Viscosity Behavior of Monoclonal Antibody Solutions

Sandeep Yadav, Thomas M. Laue, Devendra S. Kalonia et al. · Molecular Pharmaceutics · 2012 · 270 citations

High-concentration protein formulations: How high is high?

Patrick Garidel, Alexander Kühn, Lars V. Schäfer et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 175 citations

Medicine, High-concentration Protein Formulations, Protein Engineering +5

Crystalline monoclonal antibodies for subcutaneous delivery

Mark X. Yang, Bhami Shenoy, Matthew Disttler et al. · Proceedings of the National Academy of Sciences · 2003 · 161 citations · Full text

Engineering, Batch Crystallization, Biomedical Engineering +17