Concepedia

AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T <sub>H</sub> 1 response with a diverse TCR repertoire

Phillip A. Swanson, Marcelino Padilla, Wesley Hoyland, Kelly McGlinchey, Paul Fields, Sagida Bibi, Saul N. Faust, Adrian B. McDermott, Teresa Lambe, Andrew J. Pollard,

Science Translational Medicine · 2021 · 108 citations · 52 references

DOIFull text

Open access

Concepts

Abstract

Polyfunctional CD4 + and CD8 + T cell responses are elicited against the SARS-CoV-2 spike protein after two doses of the AZD1222 COVID-19 vaccine.

References

52

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi et al. · The Lancet · 2020 · 5K citations · Full text

, , +17

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

Alba Grifoni, Daniela Weiskopf, Sydney I. Ramirez et al. · Cell · 2020 · 4K citations · Full text

, , +15

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

Lisa A. Jackson, Evan J. Anderson, Nadine Rouphael et al. · New England Journal of Medicine · 2020 · 3.5K citations · Full text

, , +17

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

Jennifer M. Dan, José Mateus, Yu Kato et al. · Science · 2021 · 3K citations · Full text

, , +17

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Mingfeng Liao, Yang Liu, Jing Yuan et al. · Nature Medicine · 2020 · 2.7K citations · Full text

, , +17