Tumor-derived microparticles promote the progression of triple-negative breast cancer via PD-L1-associated immune suppression

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Gang Chen, Alexander C. Huang, Wei Zhang et al. · Nature · 2018 · 2.8K citations · Full text

Life Sciences, Immunology, Oncology +14

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Loise M. Francisco, Victor H. Salinas, Keturah Brown et al. · The Journal of Experimental Medicine · 2009 · 2K citations · Full text

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Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses

Manish J. Butte, Mary Keir, Theresa B. Phamduy et al. · Immunity · 2007 · 1.7K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Molecular Determinants of Response to Anti–Programmed Cell Death (PD)-1 and Anti–Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non–Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing

Hira Rizvi, Francisco Sánchez-Vega, Konnor La et al. · Journal of Clinical Oncology · 2018 · 1.4K citations · Full text

Medicine, Immunology, Oncology +17

Tumor-Infiltrating CD8⁺Lymphocytes Predict Clinical Outcome in Breast Cancer

Sahar Mahmoud, Emma C. Paish, Desmond G. Powe et al. · Journal of Clinical Oncology · 2011 · 1.4K citations · Full text

Life Sciences, Immunology, Oncology +17