Metal-Induced Fatty Acid Particle Formation Resulting from Hydrolytic Polysorbate Degradation

The Degradation of Polysorbates 20 and 80 and its Potential Impact on the Stability of Biotherapeutics

Ravuri S. K. Kishore, Sylvia Kiese, Stefan Fischer et al. · Pharmaceutical Research · 2011 · 300 citations

Natural Sciences, Biochemistry, Chemistry +14

Degradation of Polysorbates 20 and 80: Studies on Thermal Autoxidation and Hydrolysis

Ravuri S. K. Kishore, Astrid Pappenberger, Isabelle Bauer Dauphin et al. · Journal of Pharmaceutical Sciences · 2010 · 282 citations · Full text

Natural Sciences, Biochemistry, Chemistry +12

Knockout of a difficult‐to‐remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations

Josephine Chiu, Kristin N. Valente, Nicholas E. Levy et al. · Biotechnology and Bioengineering · 2016 · 204 citations

Life Sciences, Bioengineering, Biotechnology +14

[The European directorate for the quality of medicines].

A Artiges · PubMed · 2001 · 203 citations

Pharmacy, Pharmaceutical Policy, Pharmacy Practice +10

Residual Host Cell Protein Promotes Polysorbate 20 Degradation in a Sulfatase Drug Product Leading to Free Fatty Acid Particles

Nitin Dixit, Nazila Salamat‐Miller, Paul A. Salinas et al. · Journal of Pharmaceutical Sciences · 2016 · 165 citations

Life Sciences, Biochemistry, Molecular Biology +10