Concepedia

Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype

Alexander R. H. Hobby, Remus M. Berretta, Deborah Eaton, Hajime Kubo, Eric Feldsott, Yijun Yang, Alaina L. Headrick, Keith A. Koch, Marcello Rubino, Justin Kurian,

American Journal of Physiology-Heart and Circulatory Physiology · 2021 · 27 citations · 44 references

DOIFull text

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Concepts

Abstract

Cortical bone stem cell (CBSC) therapy after myocardial infarction alters the inflammatory response to cardiac injury. We found that cortical bone stem cell therapy induces a unique macrophage phenotype in vitro and can modulate macrophage/fibroblast cross talk.

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