KDM4C contributes to cytarabine resistance in acute myeloid leukemia <i>via</i> regulating the miR-328-3p/CCND2 axis through MALAT1

Abstract

Our study demonstrated that KDM4C may up-regulate MALAT1 expression, which decreases the expression of miR-328-3p. The downregulation of miR-328-3p increased the level of CCND2, which induced the Ara-C resistance in AML.