A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1

Lingling Miao, Hailan Yao, Chenggang Li, +6

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Transcriptional RegulationCytochrome P450 2E1Dual InhibitionGeneticsRna Biology +7

miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1

Man Gao, Lingling Miao, Mingxia Liu, +7

Oncotarget

Breast OncologyImmunologyPathologyCancer BiologyTumor Biology +14

Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer

Zhongqiang Guo, Tong Zheng, Baoen Chen, +30

Cancer Cell

Genitourinary CancerMedicineSmall MoleculesCancer GenomicsRadiation Oncology +4

Baicalin inhibits macrophage activation by lipopolysaccharide and protects mice from endotoxin shock

Linlin Liu, Li-kun Gong, Hui Wang, +6

Biochemical Pharmacology

InflammationImmunotoxicologyMacrophage ActivationMedicineImmunology +5

Long Noncoding RNA HOTAIR Modulates MiR-206-mediated Bcl-w Signaling to Facilitate Cell Proliferation in Breast Cancer

Wei Ding, Jin Ren, Hui Ren, +1

Scientific Reports

Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity

Ying Xiao, Ming Ge, Xiang Xue, +12

Kidney International

Kidney ToxicityBiochemistryMedicineLiver PhysiologyPhysiology +9

Critical Role of Organic Anion Transporters 1 and 3 in Kidney Accumulation and Toxicity of Aristolochic Acid I

Xiang Xue, Li-kun Gong, Kazuya Maeda, +4

Molecular Pharmaceutics

Aristolochic AcidRenal InflammationOxidative StressSevere Kidney InjuryRenal Function +17

The miR-491-3p/Sp3/ABCB1 axis attenuates multidrug resistance of hepatocellular carcinoma

Yang Zhao, Xinming Qi, Jing Chen, +8

Cancer Letters

Tumor BiologyMedicineMicrorna DetectionCancer BiologyCell Biology +2

Emodin Triggers DNA Double-Strand Breaks by Stabilizing Topoisomerase II-DNA Cleavage Complexes and by Inhibiting ATP Hydrolysis of Topoisomerase II

Yan Li, Yang Luan, Xinming Qi, +9

Toxicological Sciences

LncRNA H19-elevated LIN28B promotes lung cancer progression through sequestering miR-196b

Jin Ren, Jinling Fu, Tiangang Ma, +4

Cell Cycle

Tumor BiologyTranscriptional RegulationLung InflammationLncrna H19-elevated Lin28bLncrna H19 +13