Albendazole inhibits NF-κB signaling pathway to overcome tumor stemness and bortezomib resistance in multiple myeloma

A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma

Paul G. Richardson, Bart Barlogie, James R. Berenson et al. · New England Journal of Medicine · 2003 · 2.6K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

Vito J. Palombella, Oliver J. Rando, Alfred L. Goldberg et al. · Cell · 1994 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +11

Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma

Christina M. Annunziata, R. Eric Davis, Yulia N. Demchenko et al. · Cancer Cell · 2007 · 949 citations · Full text

Medicine, Genetics, Molecular Biology +13

Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B

Dharminder Chauhan, Hiroshi Uchiyama, Yasmin Akbarali et al. · Blood · 1996 · 568 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells

Teru Hideshima, Hiroshi Ikeda, Dharminder Chauhan et al. · Blood · 2009 · 371 citations · Full text

Medicine, Cell Biology, Oncology +12