Concepedia

Synthesis, docking, machine learning and antiproliferative activity of the 6-ferrocene/heterocycle-2-aminopyrimidine and 5-ferrocene-1H-Pyrazole derivatives obtained by microwave-assisted Atwal reaction as potential anticancer agents

Éclair Venturini Filho, Jorge W.S. Pina, Mariana K. Antoniazi, Laiza B. Loureiro, Marcos A. Ribeiro, Carlos B. Pinheiro, Celina J. Guimarães, Fátima C.E. de Oliveira, Cláudia Pessoa, Alex Gutterres Taranto,

Bioorganic & Medicinal Chemistry Letters · 2021 · 22 citations · 34 references

DOI

Concepts

References

34

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

Oleg Trott, Arthur J. Olson · Journal of Computational Chemistry · 2009 · 37.1K citations · Full text

, , +17

DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis

Thomas Sander, Joël Freyss, Modest von Korff et al. · Journal of Chemical Information and Modeling · 2015 · 1.8K citations

, , +17

On the medicinal chemistry of ferrocene

M.F.R. Fouda, Mokhles M. Abd‐Elzaher, Rafeek A. Abdelsamaia et al. · Applied Organometallic Chemistry · 2007 · 458 citations

, , +7

Substituted 1,4-dihydropyrimidines. 3. Synthesis of selectively functionalized 2-hetero-1,4-dihydropyrimidines

Karnail S. Atwal, George C. Rovnyak, Brian C. O'Reilly et al. · The Journal of Organic Chemistry · 1989 · 365 citations

, , +9

Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer

Daniel P. Sutherlin, Linda Bao, Megan Berry et al. · Journal of Medicinal Chemistry · 2011 · 217 citations · Full text

, , +13