Koumine modulates spinal microglial M1 polarization and the inflammatory response through the Notch-RBP-Jκ signaling pathway, ameliorating diabetic neuropathic pain in rats

Prevalence and Characteristics of Painful Diabetic Neuropathy in a Large Community-Based Diabetic Population in the U.K.

Caroline A. Abbott, Rayaz A. Malik, E. R. E. Van Ross et al. · Diabetes Care · 2011 · 856 citations · Full text

Medicine, Neurology, Diabetology +15

Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

Haixia Xu, Jimmy Zhu, Sinéad M. Smith et al. · Nature Immunology · 2012 · 438 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain

Somsak Mitrirattanakul, Navapoln Ramakul, André Vinicius Pires Guerrero et al. · Pain · 2006 · 203 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Activation of dorsal horn microglia contributes to diabetes‐induced tactile allodynia via extracellular signal‐regulated protein kinase signaling

Makoto Tsuda, Hikaru Ueno, Ayako Kataoka et al. · Glia · 2008 · 168 citations

Life Sciences, Neurobiology, Neuroscience +17

Notch signaling modulates the activation of microglial cells

Luc Grandbarbe, Alessandro Michelucci, Tony Heurtaux et al. · Glia · 2007 · 108 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17