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Acute kidney injury (AKI) in patients with Covid-19 infection is associated with ventilatory management with elevated positive end-expiratory pressure (PEEP)

Davide Ottolina, L. Zazzeron, Letizia Trevisi, Andrea Agarossi, Riccardo Colombo, Tommaso Fossali, Mattia Passeri, Beatrice Borghi, Elisabetta Ballone, Roberto Rech,

Journal of Nephrology · 2021 · 45 citations · 24 references

DOIFull text

Open access

Abstract

The use of high PEEP in Covid-19 ICU patients is associated with a fivefold higher risk of AKI, leading to higher mortality. The cause and effect relationship needs further analysis.

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