High glucose effect on the role of CD146 in human proximal tubular epithelial cells in vitro

Niansong Wang, Ying Fan, Peihua Ni, Feng Wang, Xuping Gao, Xue Qin, Lingquan Tang

Journal of Nephrology · 2008 · 12 citations · 12 references

Abstract

CD146 might be a novel marker for RTECs, correlating with cell proliferation and cell-cell conjunctions. High glucose up-regulates both CD146 and sCD146 expression. CD146 may be a biomarker of activated RTECs, and sCD146 may have clinical value for determining severity and prognosis of diabetic nephropathy.

References

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