Concepedia

5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma

Shuni Wang, Hong Yang, Mingbo Su, Fulin Lian, Zhanqing Cong, Rongrui Wei, Yubo Zhou, Xingjun Li, Xingling Zheng, Chunpu Li,

European Journal of Medicinal Chemistry · 2021 · 25 citations · 21 references

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Chemistry: Chemical con artists foil drug discovery

Jonathan B. Baell, Michael A. Walters · Nature · 2014 · 1.1K citations · Full text

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NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming

Alex Kuo, Peggie Cheung, Kaifu Chen et al. · Molecular Cell · 2011 · 442 citations · Full text

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A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome

Keisuke Nimura, Kiyoe Ura, Hidetaka Shiratori et al. · Nature · 2009 · 378 citations

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The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

Eva Martínez-García, Relja Popovic, Dong Joon Min et al. · Blood · 2010 · 357 citations · Full text

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WHSC1, a 90 kb SET Domain-Containing Gene, Expressed in Early Development and Homologous to a Drosophila Dysmorphy Gene Maps in the Wolf-Hirschhorn Syndrome Critical Region and is Fused to IgH in t(1;14) Multiple Myeloma

Ingrid Stec, Tracy J. Wright, G.J.B. van Ommen et al. · Human Molecular Genetics · 1998 · 316 citations

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