The inhibition of NFкB signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity

NF-κB signaling in inflammation

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Life Sciences, Immunology, Pathology +17

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B.

Claudia Wahl, Susanne Liptay, G. Adler et al. · Journal of Clinical Investigation · 1998 · 740 citations · Full text

Medicine, Immunology, Pharmacology +17

Sulindac Inhibits Activation of the NF-κB Pathway

Yumi Yamamoto, Min-Jean Yin, Keng-Mean Lin et al. · Journal of Biological Chemistry · 1999 · 492 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +7

Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-κB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation

Yasunari Takada, Anjana Bhardwaj, Pravin D. Potdar et al. · Oncogene · 2004 · 310 citations

Medicine, Oncology, Pharmacology +13

Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β

Christoph K. Weber, Susanne Liptay, Thomas Wirth et al. · Gastroenterology · 2000 · 299 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15