LncRNA LINC00525 suppresses <i>p21</i> expression via mRNA decay and triplex‐mediated changes in chromatin structure in lung adenocarcinoma

Abstract

Our findings demonstrate that LINC00525 promotes the progression of LUAD by reducing the transcription and stability of p21 mRNA in concert with EZH2 and RBMS2, thus suggesting that LINC00525 may be a potential therapeutic target for clinical intervention in LUAD.