Concepedia

The tyrosine phosphatase SHP2 promotes proliferation and oxaliplatin resistance of colon cancer cells through AKT and ERK

Mengchao Yu, Chengzhen Xu, Hongwei Zhang, Jie Lun, Lei Wang, Gang Zhang, Jing Fang

Biochemical and Biophysical Research Communications · 2021 · 34 citations · 21 references

Concepts

MedicineMolecular BiologyOncologyCell SignalingMolecular OncologySignal TransductionCancer Cell SignalingCancer ProgressionColorectal CancerMalignant NeoplasmsProtein Phosphatase SignalingSignal Transduction In CancerOxaliplatin-based TherapyPhosphatase TargetsPhosphatidylinositol 3-Kinase-akt PathwayPhosphoinositide 3-Kinase-akt ActivationPhosphoinositide 3-Kinase-akt SignalingPi3 Kinase-akt SignalingTyrosine Phosphorylation Signaling

References

21

Cancer statistics, 2020

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2020 · 21.4K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

Hans‐Joachim Schmoll, Eric Van Cutsem, Alexander Stein et al. · Annals of Oncology · 2012 · 1.5K citations · Full text

Medicine, Oncology, Surgery +17

Crystal Structure of the Tyrosine Phosphatase SHP-2

Peter Hof, Scott Pluskey, Sirano Dhe‐Paganon et al. · Cell · 1998 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Protein tyrosine phosphatases in signal transduction

Benjamin G. Neel, N. K. Tonks · Current Opinion in Cell Biology · 1997 · 763 citations

Life Sciences, Biochemistry, Molecular Biology +14

Chronic Oxaliplatin Resistance Induces Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cell Lines

Anthony D. Yang, E. Ramsay Camp, George Van Buren et al. · Clinical Cancer Research · 2006 · 526 citations

Medicine, Cell Biology, Oncology +17