REVIEW ON: TASTE MASKING APPROACHES AND EVALUATION OF TASTE MASKING

Abstract

Oral administration of pharmaceuticals is one of the most popular method of drug dilevery. Many orally administered drugs elicit bitter taste. Taste masking becomes a prerequisite for bitter drugs to improve the patient compliance especially in the pediatric and geriatric population. Formulating orodispersible, melt in mouth, buccal tablet and other formulations which comes in contact with taste buds taste is one of critical factor to be consider. Masking the bitter taste of drugs is a potential tool for the improvement of patient compliance which intern decides the commercial success of the product. This paper reviews different methods are available to mask undesirable taste of the drugs, with the applications. It includes adding sugars, flavors, sweeteners, use of aminoacids, coating drug, multiple emulsion, viscosity modifier, vesicles and liposomes, prodrug and salt formation, inclusion and molecular complexes, solid dispersion, application of Ion Exchange Resins (IERs).