Concepedia

CXCL1 Regulated by miR-302e Is Involved in Cell Viability and Motility of Colorectal Cancer via Inhibiting JAK-STAT Signaling Pathway

Biyin Chen, Li Song, Xiuzhen Nie, Fangfeng Lin, Zongyang Yu, Wencui Kong, Xiaoyan Qi, Wenwu Wang

Frontiers in Oncology · 2021 · 38 citations · 22 references

DOIFull text

Open access

Abstract

CXCL1 could be regulated by miR-302e to inactivate JAK-STAT signaling pathway, in turn affecting cell proliferation, migration, invasion, and apoptosis of CRC. Our result provides a potential therapeutic target for CRC treatment.

References

22

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram et al. · CA A Cancer Journal for Clinicians · 2018 · 86.6K citations · Full text

CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer

Dingzhi Wang, Haiyan Sun, Jie Wei et al. · Cancer Research · 2017 · 350 citations · Full text

Hepatic Metastasis from Colorectal Cancer

Alan I. Valderrama-Treviño, Baltazar Barrera‐Mera, Jesús Carlos Ceballos-Villalva et al. · Euroasian Journal of Hepato-Gastroenterology · 2016 · 253 citations · Full text

CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p

Xinfeng Yu, Dong Wang, Xiaohui Wang et al. · Journal of Experimental & Clinical Cancer Research · 2019 · 206 citations · Full text

Limb- and Person-Level Risk Factors for Lower-Limb Amputation in the Prospective Seattle Diabetic Foot Study

Edward J. Boyko, Amber D. Seelig, Jessie H. Ahroni · Diabetes Care · 2018 · 117 citations · Full text