Solid-state nanopore analysis of human genomic DNA shows unaltered global 5-hydroxymethylcytosine content associated with early-stage breast cancer

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

Shinsuke Ito, Li Shen, Qing Dai et al. · Science · 2011 · 3.3K citations

Chromatin, Developmental Biology, Natural Sciences +15

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Marianne Frommer, Louise E. McDonald, David Millar et al. · Proceedings of the National Academy of Sciences · 1992 · 3.2K citations · Full text

Epigenetic Change, Genetics, Dna Methylation +20

A gene hypermethylation profile of human cancer.

Manel Esteller, Paul G. Corn, Stephen B. Baylin et al. · PubMed · 2001 · 2K citations

Cancer Research, Chromatin, Epigenetic Change +14

A high-resolution recombination map of the human genome

Augustine Kong, Daníel F. Guðbjartsson, Jesús Sainz et al. · Nature Genetics · 2002 · 1.7K citations

Genetics, Genome Structure, Genomics +3

Direct detection of DNA methylation during single-molecule, real-time sequencing

Benjamin A. Flusberg, Dale R. Webster, Jessica H. Lee et al. · Nature Methods · 2010 · 1.5K citations · Full text

Chromatin, Dna Sequencing, Sequencing +10