Concepedia

Publication | Open Access

Inhibition of Secretin/Secretin Receptor Axis Ameliorates NAFLD Phenotypes

DOIFull Paper Access

39

Citations

38

References

2021

Year

Lixian Chen, Nan Wu, Lindsey Kennedy, Heather Francis, Ludovica Ceci, Tianhao Zhou, Niharika Samala, Konstantina Kyritsi, Chaodong Wu, Amelia Sybenga,
Hepatology

Abstract

The biliary SCT/SCTR/miR-125b axis promotes liver steatosis by up-regulating lipid biosynthesis gene Elovl1. Targeting the biliary SCT/SCTR/miR-125b axis may be key for ameliorating phenotypes of human NAFLD/NASH.

References

YearCitations

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