Concepedia

Publication | Open Access

Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation

11K

Citations

15

References

2021

Year

TLDR

The Interactive Tree Of Life (iTOL) is a freely available online tool for displaying, manipulating, and annotating phylogenetic and other trees. iTOL v5 introduces a completely new tree display engine with numerous new features. The new engine supports MEME motif datasets, expanded annotation options, categorical and multi‑value node metadata display, manual drawing tools, fine‑grained scale control, and a streamlined user account system that can manage over a million trees from more than 70,000 users. Unrooted tree displays can now use the equal‑daylight algorithm, providing much greater display clarity.

Abstract

Abstract The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the display, manipulation and annotation of phylogenetic and other trees. It is freely available and open to everyone. iTOL version 5 introduces a completely new tree display engine, together with numerous new features. For example, a new dataset type has been added (MEME motifs), while annotation options have been expanded for several existing ones. Node metadata display options have been extended and now also support non-numerical categorical values, as well as multiple values per node. Direct manual annotation is now available, providing a set of basic drawing and labeling tools, allowing users to draw shapes, labels and other features by hand directly onto the trees. Support for tree and dataset scales has been extended, providing fine control over line and label styles. Unrooted tree displays can now use the equal-daylight algorithm, proving a much greater display clarity. The user account system has been streamlined and expanded with new navigation options and currently handles >1 million trees from >70 000 individual users.

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