Neolignan and phenylpropanoid compounds from the resin of <i>Styrax tonkinensis</i>

Abstract

A new neolignan compound, tonkinensisin A (<b>1</b>), and two phenylpropanoid compounds, tonkinensisin B (<b>2</b>) and tonkinensisin C (<b>3</b>), were isolated from the resin of <i>Styrax tonkinensis</i> (Pierre) Craib ex Hartw. The structures of these compounds were determined by spectroscopic analysis, and the relative configurations of compounds <b>1</b> and <b>3</b> were determined by <i>J</i>-based configuration analysis (JBCA) method. All compounds were assayed for cytotoxic activities against five tumor cell lines (HepG-2, A549, Hela, MCF-7, and PC-3) by CCK-8 test <i>in vitro</i>.[Formula: see text].