Bioconjugate Chemistry · 2021 · 20 citations · 20 references
MedicineOncologyPharmacologyCancer ImmunologyImmunotherapyMolecular OncologyAntibody-drug ConjugatesCancer ImmunotherapyTargeted Cancer TherapyTargeted Radionuclide TherapyTargeted TherapyTargeting LigandsAntibody-radioisotope ConjugatesCancer Targeting LigandsConjugationMaleimide ChemistryRandom ConjugationSmall Cell Lung Cancer TreatmentTargeting Ligand ConjugationTumor Targeting Specificity
performance of the PODS-based radioimmunoconjugate and suggest that a stable, well-defined DAR2 radiopharmaceutical may be suitable for the clinical immunoPET of DLL3-expressing cancers.
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